上海肝病在线 Shanghai Liver Diseases' Online


How to carry the LAK(+APC) therapy in Shanghai?

If some one want to carry LAK(+APC)Therap,he/she must contact with us for one week ago and provide some important information about viral infection,so we can made a scheme and plan a schedule.Base on safty, The LAK(+APC) therapy is carried out in Zhongshan Hospital, Medical College, Fu-dan University.,so the LAK(+APC) therapy is not carried out in our hospital.

1)LAK(+APC)Therapy Plan

 

DATE of Therapy WEEK NO DAY OF WEEK Treatment
01~04 1`2 6、7、1、2、3 IL-2 200,000U IM QD for TLC motion into Circulation
05 2 4 Rest
06 2 5 COLLECT BLOOD for PBMC Culture IN Vitro
07~10 2~3 6、7、1、2 REST(With IL-2、PHA、GM-CSF culture PBMC to produce CTL,LAK and APC)
11 3 3 First reinfusion of LAK(+APC)
12 3 4 IL-2 200,000U IM QD for maintain the hiher antivial activity of LAK
13 3 5 Second reinfusion of LAK(+APC)
14~15 3 6-7 IL-2 200,000U IM QD for maintain the hiher antivial activity of LAK
16 4 1 Third reinfusion of LAK(+APC)
17 4 2 IL-2 200,000U IM QD for maintain the hiher antivial activity of LAK
18 4 3 Foutrh reinfusion of LAK(+APC)
19 4 4 IL-2 200,000U IM QD for maintain the hiher antivial activity of LAK
20 4 5 Fifth reinfusion of LAK(+APC)
21~22 4 6-7 IL-2 200,000U IM QD for maintain the hiher antivial activity of LAK
23 5 1 Sixth reinfusion of LAK(+APC)
24 5 2 IL-2 200,000U IM QD for maintain the hiher antivial activity of LAK
25 5 3 Seventh reinfusion of LAK(+APC)
26 5 4 IL-2 200,000U IM QD for maintain the hiher antivial activity of LAK
27 5 5 Eighth reinfusion of LAK(+APC)
28~29 5 6-7 IL-2 200,000U IM QD for maintain the hiher antivial activity of LAK
30 6 1 Ninth reinfusion of LAK(+APC)

(2)SIX Month Cytokine Therapy after LAK(+APC) Therapy to Maintain the LAK(+APC) Therapeutical Effectness and Prevent to Relaps of Viral Infection

 

WEEK MON TUE WED THU FRI SAT SUN
Treatment GM-CSF 75 Microgran SC Rest IL-2 200,000U IM Rest IL-2 200,000U IM Rest Rest